Dental problems, as a rule, accompany a person throughout his life. Many have to suffer in pain. Some decide to install implants. However, according to scientists from Japan, in the future, the need for such a procedure may disappear altogether. Teeth can not be restored artificially, but simply grown! This conclusion was reached by a group of researchers, studying the interaction of molecules responsible for the growth of tissues in the body.
The work began with observations. It turned out that animals and humans have a certain number of teeth. But in about 1% of individuals, it is slightly more or less than the norm. Scientists became interested in the causes of this phenomenon and identified certain dependences on the BMP and Wnt molecules. The USAG-1 gene, which is directly responsible for the growth of teeth, also attracted attention. But the impact on them must be careful because of the risk of side effects that were difficult to predict.
The first experiments in this direction were unsuccessful. However, scientists managed to “pick up the key” to this riddle. They found an antibody that corrected signaling between USAG-1 and BMP. Further, animal experiments followed. Using their technique, the researchers managed to grow a tooth in a laboratory mouse in just 1 session. Subsequent experiments on ferrets were also successful. Scientists plan to build on the success and further study the mechanism of tooth growth in pigs. This is necessary to assess the possibility of applying the technique in relation to a person.
So far, unambiguously, it is too early to talk about the imminent appearance of the possibility of growing teeth in dental clinics. Nevertheless, the successes achieved are great, impressive and allow us to count on the fact that in the future such technology will appear and replace existing ones involving prosthetics and the use of implants.